The earliest artifacts discovered of indigenous peoples in Panama have included Paleo-Indians projectile points. Later central Panama was home to some of the first pottery-making in the Americas, such as the Monagrillo cultures dating to about 2500-1700 BCE. These evolved into significant populations that are best known through the spectacular burials (dating to c. 500-900 CE) at the Monagrillo archaeological site, and the beautiful polychrome pottery of the Gran Coclé style. The monumental monolithic sculptures at the Barriles (Chiriqui) site are other important evidence of the ancient isthmian culture.
Prior to the arrival of Europeans, Panama was widely settled by Chibchan, Chocoan, and Cueva peoples, among whom the largest group were the Cueva (whose specific language affiliation is poorly documented). There is no accurate knowledge of size of the Pre-Colombian indigenous population of the isthmus at the time of the European conquest. Estimates range as high as two million people, but more recent studies place that number closer to 200,000. Archeological finds as well as testimonials by early European explorers describe diverse native isthmian groups exhibiting cultural variety and already experienced in using regional trade routes. The indigenous people of Panama lived by hunting, gathering edible plants & fruits, growing corn, cacao, and root crops. They lived in small huts made of palm leaves over a rounded branch structure, with hammocks hung between the interior walls for sleeping.

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Map of Mexico
History of Brazil
Ecuador Regions